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Age Gap Decision Tool

Publications

  • Observational cohort study to determine the degree and causes of variation in the rate of surgery or primary endocrine therapy in older women with operable breast cancer

    Morgan JL, Holmes G, Ward S, Martin C, Burton M, Walters SJ, Cheung KL, Audisio RA, Reed MW, Wyld L, Lifford K

    European Journal of Surgical Oncology. 2020 Sep 30

    PMID: 33046279

  • Breast Cancer Surgery in Older Women: Outcomes of the Bridging Age Gap in Breast Cancer Study

    L Morgan, J George, G Holmes, C Martin, M W R Reed, S Ward, S J Walters, K Leung Cheung, R A Audisio, L Wyld, Bridging the Age Gap Trial Management Team

    Br J Surg. 2020 Jun 2

    PMID: 32488911

  • Efficient development and usability testing of decision support interventions for older women with breast cancer

    Lifford KJ, Edwards A, Burton M, Harder H, Armitage F, Morgan JL, Caldon L, Balachandran K, Ring A, Collins K, Reed M and Wyld L

    Patient Preference and Adherence. 2019 Jan 14;13:131-143

    PMID: 30679905

  • Adjuvant chemotherapy for breast cancer in older women: An analysis of retrospective English Cancer Registration Data

    S.E. Ward, G.R. Holmes, A. Ring, P.D. Richards, J.L. Morgan, J.W. Broggio, K. Collins, M.W.R Reed and L. Wyld

    Clinical Oncology, 2019

    PMID: 31122807

  • Quality of life versus Length of life preferences in older women with early breast cancer

    Anne Shrestha, Charlene Martin, Maria Burton, Stephen Walters, Sue Ward, Geoffrey Holmes, Malcolm Reed, Karen Collins, Thompson G Robinson, Kwok-Leung Cheung, Ricardo Audisio, Jacqui Gath, Dierdre Revell, Katherine Brain, Adrian Edwards, Jenna Morgan, Tim Chater, Kirsty Pemberton, Lynda Wyld

    Psycho-oncology, 2019, Mar 5

  • How are caregivers involved in treatment decision making for older people with dementia and a new diagnosis of cancer?

    Martin C, Shrestha A, Burton M, Collins K, Wyld L

    Psychooncology. 2019 Mar 25

    PMID: 30908755

  • Omission of surgery in older women with early breast cancer has an adverse impact on breast cancer specific survival

    Ward S.E, Richards P, Morgan J, Holmes G.R, Broggio J, Collins K, Reed MW and Wyld, L

    B J Surgery, 2018

    PMID: 29790154

  • Bridging the age gap in breast cancer: evaluation of decision support interventions for older women with operable breast cancer: protocol for a cluster randomised controlled trial

    Collins K, Reed M, Lifford K, Burton M, Edwards A, Ring A, Brain K, Harder H, Robinson T, Cheung KL, Morgan J, Audisio R, Ward S, Richards P, Martin C, Chater T, Pemberton K, Nettleship A, Murray C, Walters S, Bortolami O, Armitage F, Leonard R, Gath J, Revell D, Green T, Wyld L

    BMJ Open. 2017 Jul 31;7(7):e015133

    PMID: 28760787

  • What influences healthcare professionals' treatment preferences for older women with operable breast cancer? An application of the discrete choice experiment

    Morgan JL, Walters SJ, Collins K, Robinson TG, Cheung KL, Audisio R, Reed MW, Wyld L

    Eur J Surg Oncol. 2017 Jul;43(7):1282-1287

    PMID: 28237423

  • Information needs and decision-making preferences of older women offered a choice between surgery and primary endocrine therapy for early breast cancer

    Burton M, Kilner K, Wyld L, Lifford KJ, Gordon F, Allison A, Reed M, Collins KA

    Psychooncology. 2017 Mar 23

    PMID: 28332254

  • The use of surgery in the treatment of ER+ early stage breast cancer in England: Variation by time, age and patient characteristics

    Richards P, Ward S, Morgan J, Lagord C, Reed M, Collins K, Wyld L

    Eur J Surg Oncol. 2016 Apr;42(4):489-96

    PMID: 26825007

  • The decision-making process for senior cancer patients: treatment allocation of older women with operable breast cancer in the UK

    Morgan JL, Richards P, Zaman O, Ward S, Collins K, Robinson T, Cheung KL, Audisio RA, Reed MW, Wyld L

    Cancer Biol Med. 2015 Dec;12(4):308-15

    PMID: 26779368

  • Healthcare professionals' preferences for surgery or primary endocrine therapy to treat older women with operable breast cancer

    Morgan JL, Collins K, Robinson TG, Cheung KL, Audisio R, Reed MW, Wyld L

    Eur J Surg Oncol. 2015 Sep;41(9):1234-42

    PMID: 26108734

  • Case-mix analysis and variation in rates of non-surgical treatment of older women with operable breast cancer

    Morgan J, Richards P, Ward S, Francis M, Lawrence G, Collins K, Reed M, Wyld L

    Br J Surg. 2015 Aug;102(9):1056-63

    PMID: 26095684

  • The balance of clinician and patient input into treatment decision-making in older women with operable breast cancer

    Morgan JL, Burton M, Collins K, Lifford KJ, Robinson TG, Cheung KL, Audisio R, Reed MW, Wyld L

    Psychooncology. 2015 Dec;24(12):1761-6

    PMID: 26043439

  • Understanding older women's decision making and coping in the context of breast cancer treatment

    Lifford KJ, Witt J, Burton M, Collins K, Caldon L, Edwards A, Reed M, Wyld L, Brain K

    BMC Med Inform Decis Mak. 2015 Jun 10;15:45

    PMID: 26058557

  • Surgery versus primary endocrine therapy for operable primary breast cancer in elderly women (70 years plus)

    Morgan J, Wyld L, Collins KA, Reed MW

    Updated review. Cochrane Database of Systematic Reviews 2014, Issue 5. Art. No.: CD004272

  • Primary endocrine therapy as a treatment for older women with operable breast cancer - a comparison of randomised controlled trial and cohort study findings

    Morgan JL, Reed MW, Wyld L

    Eur J Surg Oncol. 2014 Jun;40(6):676-84

    PMID: 24703110

  • Information Needs of Older Women Faced with a Choice of Primary Endocrine Therapy or Surgery for Early-Stage Breast Cancer: A Literature Review

    Burton M, Collins K, Caldon L, Wyld L, Reed M

    Curr Breast Cancer Rep (2014) 6:235–244

  • The information and decision support needs of older women (>75 yrs) facing treatment choices for breast cancer: a qualitative study

    Burton M, Collins KA, Lifford KJ, Brain K, Wyld L, Caldon L, Gath J, Revell D, Reed MW

    Psychooncology. 2015 Aug;24(8):878-84

    PMID: 25534045

CE Mark
The Age Gap Decision Tool is a software medical device that provides reference information to help a Healthcare Professional to use their knowledge to make a clinical decision.
  • The University of Sheffield
  • Cardiff University
  • Sheffield Hallam University
  • The National Institute for Health Research
  • Version 1.0
  • ©2025 The University of Sheffield
  • Built by epiGenesys

Please Note: The Age Gap on line tool uses a mathematic model based on information from many thousands of women over the age of 70 years diagnosed with early breast cancer between 2002 and 2012. Data was obtained using the UK cancer registration service. Outcomes are predicted based on the actual outcomes of these women. The model was developed on one set of data from the West Midlands and Northern and Yorkshire regions which has been subjected to peer review and published and has been validated on a second dataset to enhance accuracy and reliability. Despite this, as with any mathematical model, it may be inaccurate for an individual woman and can only provide an estimate of likely outcomes. The tool is designed to be used in consultation with an expert clinician and take into account a wide range of parameters and in collaboration with the patient and her preferences and opinions.